2007年5月7日，人们使用降胆固醇药物他汀类药物超过六个月--哪怕是烟民--就会减低患癌症风险55%，退伍军人管理局研究显示。服药为四年或以上，能降低肺癌危险性的77%。
通过得到的资料，经过6个月的使用他汀类药物，出现肺癌风险明显下降。（报告：库拉纳医师 vikas overton Brooks VA Medical Center in Shreveport及其同僚。）
这个发现，首先报道于2005年，分析来自于从1998年至2004年在八个南部各州收集的近50万份病历，最新的报告在五月号出版的杂志上。
他汀类药物的例子包括zocor（默克公司的降血脂药物），lipitor，pravachol，crestor，lescol和 Mevacor（都是各大公司的降胆固醇药品通用名）。这些药物有助于预防癌症，并不是第一次研究显示的结果。有研究显示，他汀类药物可降低人们患许多癌症的风险，包括乳癌，结肠癌，前列腺癌，脑瘤，肾癌，白血病，请研究者注意。
虽然这项研究强烈地表明，他汀类药物有助于预防癌症，但他们并不证明这些药物会减少一个人的癌症的风险。即便如此，那些肺癌的数据，依然令人信服。
库拉纳和同事们注意到：他汀类药物的保护作用[用途]对不同的年龄和种族团体，不论是否有糖尿病，吸烟和饮酒都是有效的。
虽然他汀类药物能够降低患肺癌的危险性，但并不能去除这种危险。得到肺癌的病人中，有1,994个即27.4%正在使用他汀类药物。由于他汀类药物的流行试用，肺癌甚至可以适度降低风险，并影响到大众健康，库拉纳和同事推荐。
原文：
Study: Smokers Taking Statin Drugs Get 55% Less Lung Cancer
By Daniel J. DeNoon j.denoon
WebMD Medical Newswebmd Reviewed by Louise Chang, MD,md
May 7, 2007 -- People who take cholesterol-lowering statin drugs for more than six months -- even smokers -- cut their lung cancer risk by 55%, a Veterans Administration study suggests.
Taking the drugs for four or more years cut lung cancer risk by 77%.
"The data obtained after six months of statin use clearly shows a decreasing risk for lung cancer with increasing duration of statin use," report Vikas Khurana, MD, of the Overton Brooks VA Medical Center in Shreveport, La., and colleagues.
The findings, first reported in 2005, come from an analysis of nearly half a million patient records collected from 1998 to 2004 in eight southern states.The updated report appears in the May issue of the journal Chest.
Examples of statins include Zocor, Lipitor, Pravachol, Crestor, Lescol, and Mevacor.
statinszocor,lipitor,pravachol,crestor,lescol. This isn't the first study to suggest that these drugs help prevent cancer.Studies have suggested that statins may cut a person's risk of many cancers, including breast cancer, colon cancer, prostate cancer, brain cancer, kidney cancer, and leukemia, the researchers note.
Though this research strongly suggests that the statin drugs help prevent cancer, they do not prove that taking one of these drugs will reduce a person's cancer risk. Even so, the lung cancer data are compelling.
"The protective effect of statin [use] was seen across different age and racial groups and was irrespective of the presence of diabetes, smoking, or alcohol use," Khurana and colleagues note."
While statin drugs reduced lung cancer risk, they did not eliminate it. Of the 7,280 patients who got lung cancer, 1,994 -- 27.4% -- were taking statins.
"Due to the high prevalence of statin use and the grave prognosis of lung cancer, even a modest risk reduction means a considerable effect on public health," Khurana and colleagues suggest."
SOURCES: Khurana, V. Chest , May 2007; vol 131: pp 1282-1288.
2007年5月;vol131:pp1282-1288. WebMD Medical News: "Statin Drugs Linked to Reduced Cancer Risk."webmd
原文刊登于webmd，39健康网独家翻译，未经允许，不得转载。
（责任编辑：王海娥）
